Prognostic factors affecting remission, remission duration, and survival in adult acute nonlymphocytic leukemia
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چکیده
منابع مشابه
Residual DNA methylation at remission is prognostic in adult Philadelphia chromosome-negative acute lymphocytic leukemia.
Pretreatment aberrant DNA methylation patterns are stable at time of relapse in acute lymphocytic leukemia (ALL). We hypothesized that the detection of residual methylation alterations at the time of morphologic remission may predict for worse prognosis. We developed a real-time bisulfite polymerase chain reaction assay and analyzed the methylation levels of p73, p15, and p57(KIP2) at the time ...
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Seventy-three patients with acute nonlymphocytic leukemia in first complete remission (CR) have received allogeneic bone marrow transplantation (BMT) with non-T-lymphocyte-depleted marrow obtained from matched sibling donors. The first 36 patients received a preparative regimen consisting of cyclophosphamide, 60 mg/kg/d (days -6 and -5), and 750 cGy single-dose total-body irradiation (TBI) (day...
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ژورنال
عنوان ژورنال: Cancer
سال: 1979
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(197909)44:3<1062::aid-cncr2820440339>3.0.co;2-a